Pharma Models Pre-Clinical Research Blog

11
Sep, 2014

Rodent Models and Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an inflammatory disease that attacks the joints and has plagued middle-aged and elderly generations for centuries. Despite ongoing research efforts, the cause of RA remains unknown, but it is characterized by aggressive synovial hyperplasia and inflammation. Without treatment, this leads to the destruction of joint cartilage and bone. Researchers and medical […]

09
Sep, 2014

The Clinical Need for Better Inflammatory Bowel Diseases Treatments

Imagine having abdominal cramps, inflammation, and pain along with a fever and weight loss. Individuals diagnosed with Inflammatory Bowel Diseases (IBD) suffer from these medical issues every day. The Centers for Disease Control and Prevention report that IBD is caused by chronic immune response and inflammation of the gastrointestinal tract. What occurs is the immune […]

08
Sep, 2014

Irritable Bowel Syndrome – A Complex Interplay of Biological and External Factors

According to the International Foundation for Functional Gastrointestinal Disorders (IFFGD), irritable bowel syndrome (IBS) is a condition that accounts for as much as 12% of all primary care provider visits in the United States. IBS was once widely characterized as a psychosomatic condition, with little knowledge of the underlying biology, where mental stressors were abstractly […]

04
Sep, 2014

Three Ways to Fight Chronic Lymphoblastic Leukemia

  • Posted on September 04, 2014 by Pharma Models Blogging Team in Oncology

Chronic lymphoblastic leukemia (CLL) is a common blood and bone marrow disease seen in adults. It is very rare for this disorder to affect children or adults younger than their mid-forties. Older white males are at higher risk of CLL as well as those with Eastern European Jewish descent. According to the National Cancer Institute, […]

03
Sep, 2014

How Animal Models Have Advanced Pancreatic Cancer Research

  • Posted on September 03, 2014 by Pharma Models Blogging Team in Oncology

Pancreatic cancer has one of the lowest 5-year survival rates and leads to approximately 40,000 deaths in the United States each year, the American Cancer Society reported. The survival rates of this disease are very low – only 6 percent of patients diagnosed with pancreatic cancer are alive five years later. However, incorporating animal models […]

13
Aug, 2014

A Look at Obesity and Its Lesser-Known Causes

  • Posted on August 13, 2014 by Pharma Models Blogging Team in Obesity

Overweight individuals are at a much higher risk for serious health complications including cardiovascular disease, diabetes, musculoskeletal diseases, and even cancer. According to the Centers for Disease Control and Prevention (CDC), the percentage of overweight and obese adults in the United States, aged 20 years and older totaled 69%, between 2011 and 2012. Given such […]

11
Aug, 2014

The Symptoms and Treatments of Acute Lymphoblastic Leukemia

  • Posted on August 11, 2014 by Pharma Models Blogging Team in Oncology

Leukemia is a deadly disease that affects nearly 50,000 people within the United States every year, and accounts for 65% of all childhood cancers in the US. Acute lymphoblastic leukemia (ALL) has a peak incidence between 2 and 5 years of age, and is the least common type of leukemia found in adults, according to […]

07
Aug, 2014

How Animal Models Have Improved the Study of Obesity

  • Posted on August 07, 2014 by Pharma Models Blogging Team in Obesity

Obesity has become an epidemic throughout the United States over the last decade. Medical professionals, political figures, health advocates, and even the First Lady are all attempting to put an end to the spread of obesity. The pre-clinical research sector is also studying the link between energy intake and expenditure to have a greater understanding […]

05
Aug, 2014

Chronic Myeloid Leukemia: A Cancer Not Meant for Children

  • Posted on August 05, 2014 by Pharma Models Blogging Team in Oncology

Chronic Myeloid Leukemia (CML) is a cancer of the white blood cells that forms in the bone marrow and travels through the cardiovascular system. With this particular type of leukemia, it takes much longer to develop symptoms. In fact, it may be a few years before symptoms are showing, according to The American Cancer Society. […]

30
Jul, 2014

New Diabetes Remedy: Putting a Stop to Insulin Deterioration

  • Posted on July 30, 2014 by Pharma Models Blogging Team in Diabetes

Diabetes is caused by an inability to regulate blood glucose that over time can cause life-threatening deteriorations of multiple organ systems. Due to this, diabetes is often difficult to treat. Diabetes is diagnosed by testing blood glucose levels, which are significantly higher  in diabetes patients than in the general population. Basic treatments include medications, following […]

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