Examining Human Obesity on a Molecular Level Using Murine Models of Obesity

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08
Jul, 2014

Examining Human Obesity on a Molecular Level Using Murine Models of Obesity

  • Posted on July 08, 2014 by Pharma Models Blogging Team in Obesity

Over twenty years ago, the agouti mouse was the first model cloned from which an obesity gene was described. Mutations in the agouti gene are associated with variations in coat color (stripes in cats and tigers), when an animal carries a single copy (or allele) of the gene. When the animal is homozygois for the […]

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22
May, 2014

Lessons Learned from Murine Models of Wound Healing

  • Posted on May 22, 2014 by Pharma Models Blogging Team in Diabetes, Obesity

Wound repair involves a number of highly complex biological processes that can be studied in a comprehensive manner through in vivo studies. Various murine models of wound healing have been effectively utilized to address several wound types. Hundreds of mouse models provide more validated reagents than other animals, and over 1,000 generated mutant loci, often […]

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