Cell Culture Methods and Xenografts for Modeling Breast Cancer Metastasis in Early Drug Discovery

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18
Dec, 2014

Cell Culture Methods and Xenografts for Modeling Breast Cancer Metastasis in Early Drug Discovery

  • Posted on December 18, 2014 by Pharma Models Blogging Team in Oncology

Approximately 75% of breast cancers are diagnosed as hormone positive and exhibit acceptable responses to endocrine-targeted therapies, whereas 7-15% are ER-/PR- Her2+ or ER-/PR-/HER2- – which are somewhat refractory to conventional endocrine treatment. Gene variations, different cancer subtypes, and diverse histopathologies and clinical outcomes among patients all present a challenge to currently available breast cancer […]

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21
Oct, 2014

From Breast Cancer to the Epstein-Barr Virus, Cancer Vaccines are a Game Changer

  • Posted on October 21, 2014 by Pharma Models Blogging Team in Oncology

October is National Breast Cancer Awareness Month and, as such, it is time to shed some light on important breast cancer research. In 2010, Dr. Vincent Tuohy and colleagues from the Cleveland Clinic published a paper in Nature Medicine that shows a vaccine using the target protein alpha-lactalbumin was able to prevent breast cancer in […]

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